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多孔纯钛种植体表面快速沉积钙磷涂层的研究

Fast Formation of Biomimetic Apatite Coatings on Pure Porous Titanium Implant’s Surface

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【作者】 何福明刘丽赵士芳赵姗姗陈松王小祥

【Author】 He Fuming1 Liu Li1 Zhao Shifang1 Zhao Shanshan1 Chen Song1 Wang Xiaoxiang21(The Affiliated Stomatologic Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310006, China)2(College of Materials Science and Engineering, Zhejiang University, Hangzhou 310027, China)

【机构】 浙江大学医学院附属口腔医院浙江大学材化学院 杭州310006杭州310006杭州310027

【摘要】 商业纯钛片经磨平、喷砂、清洗、酸洗后分成A、B两组。A组不作任何处理,B组用H2SO4和HCl混合液酸蚀,然后两组钛片同时置于37℃的仿生液SBF-A中1d及SBF-B中2d。结果两组钛片表面均可沉积磷灰石涂层,涂层为多孔片状结构,X射线衍射分析证实其为碳酸化羟基磷灰石和磷酸八钙的混合物,钙磷原子量比约1.51。这说明在多孔纯钛表面可以快速仿生沉积碳酸化磷灰石涂层。

【Abstract】 The aim of this study was to elaborate a dense, strong and thin calcium-phosphate coating on commercial porous pure titanium implant surface in the light of a fast biomimetic procedure. After being polished, sandblasted, cleaned and treated with the mixture of HF and HNO3, the titanium plates were divided into two groups,namely group A and group B. The specimens of group A were free from any treatment. The specimens of group B were treated with the mixture of 48%H2SO4 and 18%HCl. All specimens soaked in SBF-A solution for 1d. Then the specimens were immersed in the SBF-B solution for 2 d. A thin calcium-phosphate coating was deposited on all the specimens of the two groups,the surface consisted of well-formed crystals, which were proved to be the mixture of hydroxycarbonated apatite (HCA) and octacalcium phosphate (OCP); the coating’s Ca/P rate was 1.51. A thin carbonated calcium-phosphate coating was deposited on porous pure titanium by the use of the fast biomimetic procedure.

【基金】 浙江省医药卫生优秀青年科技人才专项科研基金资助项目(2004016);浙江省科技计划重点项目资助(200523006)
  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2007年04期
  • 【分类号】R783.2
  • 【被引频次】17
  • 【下载频次】311
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