【摘要】 在实验室条件下研究了除草剂阿特拉津对鲫鱼(Carassius auratus)的急性毒性以及在不同暴露浓度和不同作用时间下低剂量阿特拉津对雄性鲫鱼血清雌二醇含量的影响。结果表明:阿特拉津对鲫鱼的24、48和96h的LC50分别为229·33、146·17和105·94mg·L-1,安全浓度为10·59mg·L-1;长期(24d)暴露时,低浓度(0·1～5·0mg·L-1)阿特拉津对雄性鲫鱼血清雌二醇的合成具有诱导作用,且1·0mg·L-1的诱导作用最强,与对照组相比血清雌二醇含量增加了84·1%;高浓度(10·0mg·L-1)阿特拉津对雄性鲫鱼血清雌二醇的合成具有抑制作用;在5·0mg·L-1浓度下,各个处理时间的血清雌二醇含量均高于对照组,其中第14天时雌二醇含量最高,比对照组增加50%(P<0·01)。血清雌二醇含量的变化直接影响雄性鲫鱼的生殖功能和性征变化,因富集阿特拉津而导致血清雌二醇浓度发生显著变化的雄性鲫鱼可能会出现一定的生殖缺陷。更多还原

【Abstract】 The acute toxicity of atrazine to Carassius auratus and the effects of low level atrazine on serum estradiol contents in male C.auratus at different affecting time and exposure concentrations were studied under laboratory conditions.The results showed that the LC50 of atrazine to C.auratus in 24 h,48 h and 96 h was 229.33,146.17 and 105.94 mg·L-1,respectively,and the safety concentration of atrazine to C.auratus was 10.59 mg·L-1.Under long term(24 days) exposure,low concentration(0.1-5.0 mg·L-1) atrazine could induce the synthesis of serum estradiol in male C.auratus.The strongest inducing effect was happened when the concentration of atrazine was 1.0 mg·L-1,and the content of serum estradiol was increased by 84.1%,compared with the control.However,the synthesis of serum estradiol was inhibited at higher concentration(10.0 mg·L-1) of atrazine.At 5.0 mg·L-1 of atrazine,the serum estradiol content in male C.auratus at any affecting time was higher than the control,which was increased by 50% on the 14th day,reaching the highest value.The variation of serum estradiol content could directly affect the reproductive function of male C.auratus,and thus,the male C.auratus whose serum estradiol content had changed significantly due to the enrichment of atrazine in its body was likely to have reproductive problems to some extent.更多还原