【摘要】 以亚甲基兰为模型药物,选取0.1mol/L的盐酸、pH7.4的磷酸缓冲液(PBS)、生理盐水(PS)为介质,分别模拟人体的胃、肠、体液环境,考察淀粉微球的载药性能。以淀粉微球为修饰剂制作修饰碳糊电极,作为工作电极,以电活性的抗坏血酸为模型药物,采用伏安扫描法研究淀粉微球对药物的吸附机理。更多还原

【Abstract】 The drug carrying properties of starch micro-sphere were evaluated in three different media: 0.1mol/L hydrochloric acid, pH7.4 phosphate buffer succi(PBS), physiological saline(PS) with methylene blue as model drug. The adsorptive mechanism of starch micro-sphere was studied by means of eletrachemical method using ascorbic acid(AA) as model drug, using starch micro-sphere as agent prepare chemical modefied carbonic parafin electrode(CMCPE).更多还原