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新生儿硬肿症并发低血糖与胰岛细胞分泌的关系

Relationship between Newborn Hypoglycemia in Hardrdly Swelling Sickness and Islet Cell Secretion

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【作者】 李汉东王永红李志华

【Author】 Li Handong,et al(The hospital of Wuhan University of Technology Wuhan 430070)

【机构】 武汉理工大学医院武汉市第三医院儿科 武汉430070武汉430070

【摘要】 目的:研究血清胰岛素(INS)、C肽(CP)及胰高血糖素(GR)在新生儿硬肿症并发低血糖患儿的变化。方法:检测20例新生儿硬肿症并发低血糖患儿血INS、CP及GR水平,并与30例健康新生儿进行对比。结果:20例新生儿硬肿症并发低血糖患儿中血清浓度INS(10.42±2.53mμ/ml)、CP(0.17±0.18pmol/me)明显低于对照组(13.98±2.53mU/me),而观察组患儿血GR(266.2±147.54pg/ml)明显高于对照组患儿(121.13±40.98pg/ml)。观察组空腹血糖(BS)测定值与INS、CP及GR的相关系数分别为0.27、0.07、-0.03(P>0.25),观察组血INS与GR的相关系数为-0.1(P>0.05)。结论:在新生儿硬肿症中注意补充适当葡萄糖液以及皮质激素的使用,是提高血糖,维持机体需要的措施。

【Abstract】 Objective: To investigate the change of blood serum insulin、C peptide and glucagons in the newborn hypoglycemia in hardly swelling sickness.Methods: The blood serum insulin,C peptide,and GR level of 20 newborn hypoglycemia in hardly swelling sickness patients were measured and contrasted with 30 healthy newborns.Result: The blood serum density(10.42±2.53mμ/ml)and C peptide(0.17±0.18mol/ml)and obviously lower than control group(13.98±2.53mμ/ml),the glucagons(266.2±147.54pg/ml)of observation group are obviously higher than the control group’s(121.13±40.98pg/ml).The blood serum insulin,C peptide and glucagons association coefficient of observation group fasting plasma blood glucose is 0.27,(0.07) and-0.03(P<0.25),the correlation coefficient of blood serum insulin and glucoses is-0.1(P>(0.05).) Conclusion: Supplementing suitable glucose as well as using cortical hormones in the newborm hardly swelling sickness is a important measure of enhancing the blood glucose and maintenancing organism.

  • 【文献出处】 数理医药学杂志 ,Journal of Mathematical Medicine , 编辑部邮箱 ,2007年01期
  • 【分类号】R722.16
  • 【下载频次】33
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