【摘要】 原发性高血压病的发生原因和发病机理十分复杂,很多问题目前并不十分清楚。通过近几十年的研究,大家比较一致的看法是,原发性高血压病的内因是肾脏功能的损伤,其发生条件(外因)是摄取的食盐(钠)过多。人类饮食中添加食盐已有几千年的历史,它是人类文明发展的一种表现。然而各种研究的结果表明,食盐的过量摄取的确是高血压的元凶。此外,原发性高血压多见于老年人。由于有这些特点,因此原发性高血压病常常被看成是一种“文明”病,一种肾脏的疾病,一种老年人常见的病。本文将对这些特点作进一步的分析和讨论。更多还原

【Abstract】 Although the mechanisms underlying the development of essential hypertension remain elusive, many observations point to the kidney as a primary actor and sodium as the main culprit (external factor) for development of hypertension. Dietary sodium has been existed for several thousands years in human being and it seems to be a civilized food habit. However, over the last few decades, experimental, observational and clinical data have continuously indicated that excess salt intake is positively associated with elevated blood pressure. It was also found that aged people is easier to be suffered from essential hypertension. By now, essential hypertension is frequently considered as a "civilized" disease, a disease of the kidney and the disease frequently occurring in the aged people. In the present mini review these features of essential hypertension are discussed in more details.更多还原