【摘要】 目的:探讨丝裂霉素C和肝素用于小梁切除术的临床疗效。方法:采用随机对照的方法,将青光眼患者90例(150眼)分为丝裂霉素组和肝素点眼组,各75眼,行标准小梁切除术。丝裂霉素组在术中一次性应用丝裂霉素C,浓度为0.2~0.4 mg/ml,2~4 min;肝素组术后用5%肝素滴眼液点眼。随访观察6个月。结果:两组的完全成功率和条件成功率均高于标准小梁切除术,两组之间的成功率差异无统计学意义(P>0.05)。结论:在小梁切除术中应用丝裂霉素C,或术后应用肝素,均能提高手术成功率,长期保留功能性滤过泡。更多还原

【Abstract】 Objective: To explore the effect of intra-operative mitomycin C and post-operative heparin in trabeculectomy for glaucoma.Methods: One hundred and fifty eyes of ninety patients were randomly divided into the mitomycin C group and the heparin group.Mitomycin C at 0.2-0.4 mg/ml was subjected to patients of the former group for 2-4min,and 5% heparin was used in patients of the later group.Results: During a follow-up of 6 months,the success rate of the two groups was both higher than that of the standard trabeculectomy group.The difference between the two groups was not significant(P>0.05).Conclusion: Both intra-operative mitomycin C and post-operative heparin can improve the success rate and regain the functional bleb for a long time.更多还原