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鼻息肉患者和正常人群鼻腔真菌调查分析

A study fungal distribution in the nasal cavity of patients with nasal polyps and control

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【作者】 刘盛林秦作荣董全江郭建毛承深

【Author】 LIU Sheng-lin1,QIN Zuo-rong1,DENG Quan-jiang1,Guo Jian2,MAO Cheng-shen1(1.Department of Otolaryngology,Qingdao Hiser Hospital,Qingdao 266033,Shandong,China;2.Qingdao Blood Centre,Qingdao 266071,Shandong,China)

【机构】 青岛市海慈医疗集团耳鼻咽喉科青岛市中心血站青岛市海慈医疗集团耳鼻咽喉科 山东青岛266033山东青岛266033山东青岛266071

【摘要】 目的:探讨鼻息肉患者和正常人群鼻腔真菌分布情况。方法:选择青岛地区慢性鼻窦炎鼻息肉患者70例作为观察组、正常志愿者50例作为对照组,在无菌条件下分别取其鼻息肉表面分泌物和中鼻甲、中鼻道分泌物,即行涂片镜检及真菌培养,观察结果。结果:(1)观察组、对照组的鼻腔分泌物真菌培养阳性率分别为51.0%、37.7%,涂片镜检真菌阳性率分别为41.4%、34.0%;(2)在培养出的真菌中,曲霉菌属占67.4%。结论:(1)青岛地区鼻息肉患者和正常人群鼻腔真菌镜检及培养阳性率相似,差异无统计学意义;(2)在培养出的真菌中以曲霉菌属为主。

【Abstract】 Objective: To study fungal distribution in the nasal cavity of patients with nasal polyps and control.Methods: Seventy patients with chronic sinusitis and nasal polyps were enrolled in the experimental group,and fifty volunteers were enrolled in the control group.Secretions on the surface of nasal polyps were collected under sterile condition and examined under a microscope. The secretion on the surface of the middle turbinate and from the middle meatus was collected in sterilization and examined by the microscope.Results:(1) The percentage of positive fungal cultures was 51.0% and 37.7% in the experimental group and the control group,respectively.The percentage of positive fungal by examination under a microscope was 41.4% and 34% in the experimental group and the control group,respectively.(2) The percentage of positive Aspergillus species was 67.4% in the positive fungal cultures or by examination under a microscope in the experimental group and the control group.Conclusion:(1) The percentage of positive fungal by examination under a microscope and fungal cultures is similar between the experimental group and control group in the Qingdao area;(2) Aspergillus species are the major specimens in the positive fungal cultures and by examination under a microscope.

【关键词】 真菌鼻息肉
【Key words】 FungiNasal septum
【基金】 青岛市卫生局立项课题(2004-WSZD015)
  • 【文献出处】 山东大学耳鼻喉眼学报 ,Journal of Otolaryngology and Ophthalmology of Shandong University , 编辑部邮箱 ,2007年01期
  • 【分类号】R765.23
  • 【被引频次】5
  • 【下载频次】64
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