【摘要】 目的改进盐酸特拉唑嗪的合成工艺。方法以无水哌嗪为起始原料,经酰化、还原、胺化、成盐等反应制得盐酸特拉唑嗪。结果与结论降低了成本,提高了收率,适合工业化生产。更多还原

【Abstract】 OBJECTIVE To improve the synthetic procedure of terazosin hydrochloride.METHODS Terazosin hydrochloride was synthesized from anhydro-piperazine via acylation,reduction,amination,salification etc.RESULTS and CONCLUSION The new method can reduce the cost,enhance the yield,and it was suitabale for pharmaceutical industry.更多还原