【摘要】 研究了两种单席夫碱锰(Ⅲ)配合物作为模拟水解金属酶催化α-吡啶甲酸对硝基苯酚酯(PNPP)的水解动力学过程,提出了相应的PNPP催化水解的机理并建立了合理的动力学数学模型.考察了底物浓度、体系的酸度以及配体结构对PNPP催化水解反应的影响.讨论了取代基团的空间效应和疏水微环境对PNPP水解的影响.研究结果表明:此两种席夫碱锰(Ⅲ)配合物在催化PNPP水解中都表现出较好的催化活性,并且催化活性随着体系pH值和温度的增大而增大;带有吗啉悬垂修饰基团的席夫碱锰(Ⅲ)配合物具有比带有苯并氮杂-15-冠-5修饰基团的席夫碱Λ锰(Ⅲ)配合物更高的催化活性.更多还原

【Abstract】 Two Schiff base Mn(Ⅱ) complexes,which respectively contains benzoaza-15-crown-5 and morpholine pendants,have been employed to catalyze the hydrolysis of p-nitrophenol picolinate under a variety of conditions.Specially,effecst of steric hindrance and hydrophobic action of substitutes on PNPP hydrolytic rate have been investigated.The obtained results reveal that the one complex containing morpholine groups exhibits higher catalytic activity over another one containing benzoaza-15-crown-5.Moreover,the hydrolysis rates of PNPP increase with increasing pH values and temperatures.更多还原