【摘要】 建立乳腺腺泡模型和初步探讨其形成机理,为深入研究血乳屏障和泌乳机理提供基础方法和基本手段;采用改良的EHS基质培养法;成功获得具有极性和分泌功能的小鼠乳腺模型,向腺泡腔内可分泌β-酪蛋白和IGFBP-5;获得的小鼠乳腺腺泡模型具有显著的腔内分泌功能。更多还原

【Abstract】 The acinar model of mammary gland was established and its mechanism was explored to provide the basic methods and fundamental means for studying on blood milk barrier and lactating mechanism; The improved EHS medium culture was used; The polar acinar model of mice mammary gland with secreting function was gotten successfully, and the β-casein and IGFBP-5 were secreted into acinar cavity; The acinar model of mice mammary gland has remarkably secreting function into acinar cavity.更多还原