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甲状腺激素辅助治疗儿童肾病40例分析

Analysis of results in support treatment of 40 infantile nephropathy cases with thyroid hormone

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【作者】 张煜华侯继文马远平

【Author】 ZHANG Yi-hua, HOU Ji-wen, MA Yuan-ping. (Meizhou Municipal People’s Hospital, Meizhou 514031, Guangdong, P.R. China)

【机构】 梅州市人民医院儿科梅州市人民医院儿科 广东梅州514031广东梅州514031

【摘要】 目的探讨小剂量甲状腺激素辅助治疗儿童肾病综合征(INS)的疗效。方法将78例甲状腺激素水平低下的肾病患儿随机分为治疗组(n=40)和对照组(n=38),治疗组在常规治疗上加用甲状腺激素,4周后观察症状改善情况,9月后观察疗效。结果治疗组症状改善明显高于对照组(P<0.05),疗程结束后2组有效率无明显差异(P>0.05)。结论加用小剂量甲状腺激素能改善肾病综合征患儿的症状,但对治疗有效率无明显提高。

【Abstract】 Objective To explore the effect of small-dose-thyro-oxyindole used as auxiliary treatment on nephropathy syndrome in children. Methods There 78 thyropenia children suffering from kidney disease were divided into two treatment group consisted of 40 cases treated with conventional therapy plus thyroid hormone and the results were observed 4 and 9 months after treatment and control group consisted of 38 cases treated with conventional therapy. Results The marked improvement of symptoms was observed in the treatment group compared to the control group 4 months after treatment (P<0.05). But there no significant difference in effective rate between the two groups 9 months after treatment was observed (P>0.05). Conclusion Conventional therapy plus small-dose-thyro-oxyindole can improve the symptoms of the children suffering from kidney disease, however the therapeutic effect is not markedly superior to conventional one.

【关键词】 甲状腺激素儿童肾病综合征
【Key words】 Thyroid hormoneChildrenNephropathy
  • 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2007年03期
  • 【分类号】R726.9
  • 【被引频次】8
  • 【下载频次】30
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