【摘要】 目的了解温州市健康人群乙型肝炎感染情况及免疫水平,为实施对健康人群乙肝疫苗免疫计划和乙肝的防治提供依据。方法对2003～2005年间来温州市疾病预防控制中心体检的健康人群,采用酶联免疫吸附试验(ELISA)进行HBsAg、HBeAg,对HBsAg阳性者用金标快速诊断试剂进行复检。结果共检测了89 639例,HBsAg阳性者4 902人,总阳性率5．47%,HBeAg阳性率1．58%(1 397/89 639)。其中,学生体检数38 501例,HBsAg阳性者2 236人,阳性率5．81%；一般从业人员7 428人,HBsAg阳性者689,阳性率9．28%；服务行业从业人员43 710例,HBsAg阳性者1 977人,阳性率4．52%。结论不同人群的乙肝感染率有很大区别,学生和餐饮服务行业人员的感染率相对较低,并呈逐年下降趋势；普通人群中乙肝感染率还是较高,3年没有很大改变,说明温州市的乙肝疫苗接种有很大的效果,但还应及时对易感人群接种乙肝疫苗,减少乙肝发病率。更多还原

【Abstract】 Objective To understand infectious status HBV and immunization level in the populations in Wenzhou City and pro- vide the basis for making vaccination plan and control program.Methods HBsAg and HBeAg in the population were determined with ELISA from 2003 to 2005 and those positive for HBsAg were reexamined with golden marker fast diagnosis reagent.Results Altogether 89 639 examples were determined and 4902 HBsAg positives were detected with a positive rate of 5.47%(4 902/89 639) and the HBeAg positive rate was 1.58%(1 397/89 639).The positive rates in student,general population and service workers were 5,81%(2 236/38 501),9.28%(689/7 428)and 4.52%(1 977/43 710),respectively.Conclusion The infection rates of HBV vary greatly in different population showing a lowering tendency year after year.The positive rate of HBV in the general popula- tion is still high.Thus timely vaccination of hepatitis B vaccine targeting susceptible population be performed to reduce the incidence of hepatitis B.更多还原