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肝病患者凝血象和红细胞参数检测的临床意义

Clinical significance of coagulation parameters,platelet parameters and erythrocyte parameters in hepatopathy patients

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【作者】 陈梅; 傅玉如; 方伟祯; 鲍蕴文;

【Author】 CHEN Mei FU Yu-ru FANG Wei-zhen (The Laboratory Department,Second AfFiliated Hospital of Sun YetSen University,Guangzhou 510120,Guangdong,P.R.China)

【机构】 中山大学第二附属医院; 中山大学第二附属医院 广东 广州 510120; 广东 广州 510120;

【摘要】 目的了解肝病患者凝血象和红细胞参数的变化,并探讨其临床意义。方法对85例肝病患者进行凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)四项凝血指标测定,并同时进行平均红细胞体积(MCV)、红细胞体积分布宽度(RDW)和血小板计数(PLT)的检测。结果85例肝病患者测定结果表明,PT、TT、APTT均较对照组明显延长(P<0.05),除肝癌外,FIB均较对照组明显减低(P<0.05)。除急黄肝MCV与对照组差异无显著性外,其他各项差异均有显著性(P<0.05)。结论肝病患者血液患者血液处于明显的低凝状态,提示及时对肝病患者进行凝血因子的检测,有利于预防继发性出血,指导临床治疗,避免并发症的发生。

【Abstract】 Objective To analyze clinical significance of coagulation parameters,platelet parameters and erythocyte parameters in occurrence of hepatopathy patients.Methods Prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),fibrinogen(FIB) and mean corpuscular volume(MCV),RBC distribution width(RDW),blood platelet count(BPC) in 85 hepatopathy patients were determined.Results The PT,APTY,Tr in 85 cases of hepatopathy patients were longer than those in the control group (P<0.05)and the value of FIB were reduced except in the hepatic carcinoma ptients (P<0.05).There was significant difference in the value of MCV,RDW,BPC between the patients and control group except the value of MCV in severe icteric hepatits patients (P<0.05).Conclusion The coagulation parameters in hepatopathy patients were in a state of low coag- ulation,suggesting that the determination of coagulation parameters,platelet parameters and erythroeyte parameters is helpful for pre- venting secondary bleeding and complications as well as guiding clinical treatment.

  • 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2007年01期
  • 【分类号】R575
  • 【被引频次】8
  • 【下载频次】90
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