【摘要】 为了探讨高温碘油联合热化疗药物的血管栓塞及热杀伤作用对原发性巨块型肝癌的疗效,采用Seldinger改良技术将导管超选择插入肿瘤供血动脉后行110℃碘油栓塞联合热化疗药物灌注,使肿瘤达到Ⅳ级栓塞标准。58例患者治疗成功,肿瘤均呈不同程度缩小,术后临床不良反应轻,肝功能损害不明显,生存期较长。初步研究结果提示,高温稀释碘油联合热化疗药物对肿瘤滋养血管栓塞彻底,对肿瘤细胞热杀伤作用增强,不良反应轻,治疗原发性巨块型肝癌疗效好。更多还原

【Abstract】 The objective of this study was to explore the curative effects of the combined use of hyperthermal lipiodol,anticancer drug and thermocoagulation in the treatment of massive hepatocarcinoma.According to the modified technique of Seldinger methods,the catheter was placed into the target vessel and then hyperthermal lipiodol at 110 ℃ and anticancer drugs were perfused into the vessel so as to be up to the standard of Ⅳ embolism.Fitly-eight cases succeeded with different extent of reduction of carcinoma,mild side effects,slight impairment of liver function and long survival time.Hyperthermal dilute lipiodol combined with hyperthermal anticancer drugs can block the nutrient artery of tumor thoroughly and kill tumor cells effectively with mild side effects,and therefore,can produce good effects on massive hepatocarcinoma.更多还原