【摘要】 为了探讨影响染料法乳腺癌前哨淋巴结活检(SLNB)成功率的因素及其可能机制,使用亚甲蓝染色法对89例乳腺癌进行SLNB,分析其可能的影响因素和机制。结果:78例成功检出前哨淋巴结(SLN),检出率为87.6%。术前未触及肿大淋巴结者,SLN检出率明显高于可触及肿大淋巴结者(P<0.05),而假阴性率显著低于后者,P<0.05;实验后期64例SLNB检出率高于实验早期25例的检出率,P<0.05。初步研究结果提示,腋窝淋巴结肿大影响SLNB的检出率;SLNB技术学习曲线也可影响SLN的检出率。SLNB可用于指导乳腺癌的外科治疗。更多还原

【Abstract】 The objective of this study was to explore the factors that might affect the success rate of sentinel lymph node biopsy(SLNB)with living dye in patients with breast cancer.Eighty-nine patients with breast cancer were detected for sentinel lymph nodes(SLN)by using methylene blue,and the possible factors that might affect the success rate of SLNB and the mechanisms were analyzed.Seventy-eight cases(87.6%)were confirmed by SLNB.The rate of detection of SLN with palpable axillary node(s)was lower(P<0.05),while the pseudo-negative rate was higher than that with no palpable axillary nodes,P<0.05.The rate of detection of SLN in the first 25 cases was lower than that in the latter 64 patients,P<0.05.In conclusion,the enlarged axillary node may affect the success rate of SLNB.The rate of SLN detection could be improved by repeated practice.SLNB can direct the surgical treatment of breast cancer.更多还原