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球囊导尿管自助式扩张治疗食管与贲门癌术后吻合口顽固性狭窄

Treatments of the patients with pertinacity anastomotic-stenosis after esophageal and/or gastric cardiac cancer with balloon foley catheter

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【作者】 高社干王立东冯笑山郭琳陈书昌乔滨马保根

【Author】 GAO She-gan1,2, WANG Li-dong1, FENG Xiao-shan1,2, GUO Lin2, CHEN Shu-chang2, QIAO Bin2, MA Bao-gen31. Laboratory for Cancer Research, Experimental Center for Medicine, Henan Key Laboratory for Esophageal Cancer,Zhengzhou University, Zhengzhou 450052, P.R.China2. Department of Oncology, First Affiliated Hospital of Henan University of Science and Technology, Luoyang471003, P.R.China3.Department of Oncology People’s Hospital of Henan Province, Zhengzhou 450003, P.R.China

【机构】 郑州大学医学实验中心癌症研究室 河南省食管癌重点开放实验室郑州大学医学实验中心癌症研究室河南省食管癌重点开放实验室河南科技大学第一附属医院肿瘤科河南省人民医院肿瘤科河南郑州450052河南科技大学第一附属医院肿瘤科河南洛阳471003河南郑州450052河南郑州450003

【摘要】 目的:探讨内镜下微波高温凝固联合Savary-Gilliard探条及球囊导尿管自助式扩张对食管/贲门癌术后吻合口顽固性狭窄的疗效。方法:对40例食管/贲门癌术后吻合口顽固性狭窄患者进行微波高温凝固联合探条及球囊导尿管自助式扩张,治疗后跟踪观察吻合口狭窄改善情况。结果:治疗1个月后有效率(CR+PR)为87.5%(35/40),3个月后为82.5%(33/40),两者比较差异无统计学意义,χ2=0.392,P=0.531;6个月后为70.0%(28/40),与治疗后1个月比较差异无统计学意义,χ2=3.660,P=0.056。结论:球囊导尿管自助式扩张是预防内镜下微波高温凝固联合探条扩张治疗食管/贲门癌术后吻合口狭窄后再狭窄的有效方法。

【Abstract】 OBJECTIVE:To determine the efficacy of microwave tissue coagulation combined with “Savary-Gilliard” rod dilation via endoscope and self-help dilation with balloon foley catheter in the treatment of pertinacity anastomotic-stenosis after esophageal and/or gastric cardiac cancer operation. METHODS: Fourty patients with pertinacity anastomotic-stenosis after esophageal and/or gastric cardiac cancer operation were performed the expanding therapy by microwave tissue coagulation combined with “Savary-Gilliard” rod dilation and self-help dilation with balloon foley catheter. Then, the improvement of anastomotic-stenosis was observed following the treatment. RESULTS: The effective rates (CR+PR) of dilation were 87.5%(35/40) in one month after treatment, 82.5%(33/40) in three month after the treatment (compared with the one month after the treatment, χ2=0.392,P=0.531, 70.0%(28/40) in six month after the treatment (compared with the one month after the treatment, χ2=3.660,P=0.056. CONCLUSION: The therapy of self-help dilation with balloon foley catheter is a good choice to prevent strait again after the treatment in microwave tissue coagulation combined with “Savary-Gilliard” rod dilation to anastomotic-stenosis after esophageal and/or gastric cardiac cancer operation.

【基金】 国家自然科学基金(30670956);国家杰出青年科学基金(30025016);河南省医学科技创新人才工程基金(20040055)
  • 【文献出处】 中华肿瘤防治杂志 ,Chinese Journal of Cancer Prevention and Treatment , 编辑部邮箱 ,2007年01期
  • 【分类号】R735
  • 【被引频次】1
  • 【下载频次】64
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