【摘要】 以对苯二酚、2-氯-5-三氟甲基吡啶为原料通过先醚化得到4-(5-(三氟甲基)吡啶-2-苯氧基)苯酚,再与R-甲磺酰乳酸丁酯进行醚化反应得到吡氟禾草灵,所得产物化学结构经核磁共振谱、质谱等确证。反应总收率在42.0%以上,含量(HPLC)达93.0%。更多还原

【Abstract】 Fluazifop-butyl was synthesized by the reaction of hydroquinone with 2-chloro-5-tri-fluoromethylpyridine and replacing R-butyl-2-chloropropanate with (R)-butyl 2-(methylsulfonyloxy)propanoate in the following etherifi- cation reaction. The structure of target compound was confirmed by 1H NMR and MS. Total yield is above 42.0%, and purity determined by HPLC is 93.0%.更多还原