【摘要】 为了寻找高效、安全的杀菌活性化合物,设计并合成了8个N-(4,6-二取代嘧啶-2-基)苯甲酰胺类化合物,其化学结构经1HNMR、IR、LC/MS和元素分析确证。初步生物活性测定结果表明,该类化合物具有一定的杀菌活性,当浓度为25mg/L时,化合物4g对稻瘟病菌Pyricularia oryzae的抑制率达85.1%,化合物4f对小麦赤霉病菌Gibberella zeae的抑制率达92.9%。更多还原

【Abstract】 In search of safer and more effective fungicidal compounds,eight N-(4,6-disubstitued pyrimidin-2-yl)-benzamides were designed and synthesized.Their structures were confirmed by IR,1H NMR,LC/MS and elemental analysis.Preliminary bioassay showed that some of the title compounds showed good fungicidal activity,for example,4g exhibited 85.1% inhibition rate to Pyricularia oryzae at 25 mg/L and 4f exhibited 92.9% inhibition rate to Gibberella zeae at 25 mg/L.更多还原