【摘要】 目的探讨超细粉碎对黄芪有效成分溶出的影响。方法采用高频振动粉碎的方式对黄芪进行超细粉碎,在黄芪达到破壁的情况下,测定其有效成分。结果超细粉碎后的黄芪有效成分黄芪多糖和皂苷的溶出量及黄芪多糖单位时间的溶出速率明显高于初级粉碎品。结论将黄芪进行破壁粉碎后,有效成分直接暴露于溶剂中,有利于提取。更多还原

【Abstract】 ObjectiveTo explore the influence of superfine grind process on dissolving behavior of effective component of Astragalus membranaceus(Fisch).Bge.MethodsRadix Astragali had been grinded by high frequency vibrated mill with the grind size about 10-30μm.The effective component was measured after the cell was broken.ResultsThe dissolving-out amount and dissolving speed of effective component such as APS(Astragali Polysaccharide) and Astragalosde,were increased comparing with coarse particle.ConclusionWhen the cell wall has been broken,the effective component could be exposed directly in solvent,which is benefit with exaction.更多还原