【摘要】 目的观察盐酸替罗非班对ST段抬高急性心肌梗死(STEMI)患者急诊经皮冠状动脉介入治疗(PCI)中TIMI血流的影响。方法选择急诊入院STEMI患者43例,随机分为盐酸替罗非班组23例和对照组20例。替罗非班组PCI术前开始应用盐酸替罗非班,持续泵入至术后36-48小时。对照组应用常规PCI。收集所有病例的临床和冠状动脉造影资料,观察PCI术前、术后TIMI血流情况。结果替罗非班组急诊PCI术后TIMI血流3级的发生率较对照组差异有统计学意义(P<0.05)。结论替罗非班可改善STEMI患者梗死相关血管的TIMI血流。更多还原

【Abstract】 ObjectiveTo investigate the effects of Tirofiban on TIMI flow in patients with ST segment elevation acute myocardial infarction(STEMI) during emergency percutaneous coronary intervention(PCI).MethodsForty-three patients with STEMI who underwent emergency PCI were randomly divided into Tirofiban group(n=23) and control group(n=20).Tirofiban was used in the former group before operation and continued for 36-48 hours after PCI.In the latter group,PCI was performed through routine process.The TIMI flow was observed angiographically before and after the operation.ResultsNinety-four percent patients in the Tirofiban group were recovered with TIMI 3 grade flow.In the control group eighty-nine percent patients restored TIMI 3 grade flow.The difference was found to be statistically significant(P<0.05).ConclusionTirofiban may improve TIMI flow in patients with STEMI during emergency PCI.更多还原