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植物磷酸化蛋白质组学的研究进展
Research Progress on Plant Phosphoproteomics
【摘要】 蛋白质的磷酸化是一种最重要的蛋白质翻译后修饰方式之一。蛋白质的磷酸化和去磷酸化在生命过程中起着关键的调节作用。当前,磷酸化蛋白质组学的主要研究内容包括鉴定磷酸化蛋白、定位磷酸化位点、定量磷酸化水平,进而揭示磷酸化和去磷酸化在生命过程中所起的生物学功能。在介绍植物磷酸化蛋白组学的研究方法及目前进展的基础上,展望了植物磷酸化蛋白组学的研究前景。
【Abstract】 Protein phosphorylation is the most important mode of post-translational modifications.Protein phosphorylation and dephosphorylation play a critical regulation function in the whole process of vital movement.The major objectives of the present phosphoproteomics include the isolation of global phosphorylation protein in the cell,the generation of global phosphorylation protein map,and the identification of phosphorylated site on phosphorylation protein,and then regulation functional analysis of phosphorylation and dephosphorylation in the life process.On the basis of introducing the research approaches and the latest progress on plant phosphoproteomics,this paper also looks into the prospects of phosphoproteomics.
【Key words】 plant; phosphorylation; phosphoproteome; mass spectrometry; isolation and identification;
- 【文献出处】 中国农业科技导报 ,Journal of Agricultural Science and Technology , 编辑部邮箱 ,2007年04期
- 【分类号】Q946
- 【被引频次】13
- 【下载频次】1136