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低声压动态超声造影技术对肝脏局灶性病变诊断价值的研究

Clinical evaluation of contrast-enhanced ultrɑsonogrɑphy with low acoustic pressure in the differential diagnosis of focal liver lesion

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【作者】 张伟民胡建群包作伟周敏华储立成储仁华

【Author】 ZHANG Wei-min*, HU Jian-qun, BAO Zuo-wei, ZHOU Min-hua, CHU Li-cheng, CHU Ren-hua (Department of Ultrasonic Diagnosis, the First Affiliated Hospital of NJMU, Nanjing 210029, China)

【机构】 南京医科大学第一附属医院超声科南京医科大学第一附属医院超声科 江苏南京210029江苏南京210029

【摘要】 目的:评价低声压超声造影技术在肝占位性病变中的鉴别诊断价值。方法:应用Sonovue超声造影剂对181例共209个肝脏病灶行超声造影,并对造影结果进行分析。病灶经病理证实或随访6 ̄12个月证实。结果:144个原发性肝细胞性肝癌(HCC)病灶和血管肉瘤、胆管细胞癌、结核各1个病灶呈现“快进快出”模式;25个血管瘤病灶呈现“慢进慢退”;21个肝硬化不典型增生结节,动脉期无增强,门脉期增强;5例转移性肝癌均为快速廓清,但动脉相增强方式不同;1例FNH和炎性假瘤呈“快进慢出”;5例脓肿为快速融合性增强;3例炎性假瘤2例结核未见造影增强。结论:低声压超声造影技术对肝脏局灶性病变定性诊断提供一种选择模式,超声造影较CDFI可显著提高局灶性肝脏病变的发现和定性诊断率。

【Abstract】 Objective: To evaluate the value of contrast-enhanced ultrasonography with low acoustic pressure in differential diagnosis of focal liver lesion. Methods:181 cases with 209 focal liver lesions underwent contrast-enhanced ultrasonography(CEUS) and the results were analyzed retrospectively. The lesion was confirmed by pathology or follow-up for 6-12 months. Results:144 cases of HCC, 1 case of angiosarcoma, 1 case of cholangiocellular carcinoma(CCC) and 1 case of hepatic tuberculosis(HTB) showes an enhancement pattern of “fast-in and fast-out”, 25 cases of haemangioma showing “slow-in and slow-out”, 21 nodules of adenomatous hyperplasia in cirrhotic patients showing no enhancement in the arterial phase. In the portal phase, the echogenicity increased and the lesion became isoechoic compared to the surrounding liver parenchyma. Five cases of metastasis showed a pattern of “fast out”, 1 case of focal nodular hyperplasia(FNH) and 1 case of inflammatory pseudotumor(IPT) showing“fast-in and slow-out”. Five cases of liver abscess showed quick indiscrete haphazard enhancement, and 3 cases of IPT and 2 cases of HTB showing no enhancement. Conclusion:CEUS is a choice for characterization of liver focal lesions. Compared to CDFI, CEUS, can dramatically improve the ability to find and characterize focal liver lesions.

【基金】 常州市卫生局科技项目[常卫科教(2003)291]
  • 【文献出处】 南京医科大学学报(自然科学版) ,Acta Universitatis Medicinalis Nanjing(Natural Science) , 编辑部邮箱 ,2007年01期
  • 【分类号】R445.1
  • 【被引频次】9
  • 【下载频次】83
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