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血清激活素A对胎儿窘迫的预测价值

The Predictive Value of Active A as a Index on Fetal Distress

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【作者】 谭景邵玉琴黄小艺李文峰

【Author】 TAN Jin, SHAO Yu-qin, HUANG Xiao-yi,et al. Department of Obstetrics and Gynecology, The People-s Hospital of Zhuhai, Zhuhai, 519000

【机构】 广东省珠海市人民医院产科广东省珠海市人民医院检验科 (519000)(519000)

【摘要】 目的:探讨分娩时母血、脐血的激活素A(ACTA)水平预测胎儿窘迫的意义。方法:对335例正常产妇分娩前30min内抽取肘静脉血检测乳酸(LA)、ACTA水平,分娩时测定脐动脉血气pH值以及母、脐血ACTA和LA值,结合羊水性状和新生儿1minApgar评分情况,分析它们之间的关系。结果:母血、脐血ACTA水平与pH值呈显著负相关(r=-0.834,r=-0.657,P<0.01),优于LA水平(r=-0.393,r=0.718,P<0.01);母血、脐血中ACTA水平和脐血LA水平,酸血症组和窒息组较正常组差异显著,P<0.01,而母血中LA水平差异不显著,P>0.05;母血ACTA水平仅在羊水清亮组与Ⅲ度浑浊组之间有明显差异P<0.05;其余各羊水不同性状组间的ACTA和LA值均无明显差异,P>0.05。结论:母血、脐血ACTA水平对胎儿窘迫的预测价值明显优于LA,可作为预测胎儿窘迫的一个新敏感指标。

【Abstract】 Objective: To assess the value of active A (ACTA) as a new index on fetal distress. Methods: Data were collected from 335 normal pregnancies who were a1l near term and singleton gestation.Umbilical cord arterial blood gas was analyzed at birth. At the same time,the levels of ACTA and lactic acid in the maternal and umbilical serum were measured. Results: The levels of ACTA in the maternal and umbilical serum had significantly negative relationship with the umbilical arterial blood gas pH respectively (r=-0.834,r=0.657,P < 0.01), also the level of lactic acid has negative relationship(r=-0.383,r=-0.718,P < 0.01). The ACTA of maternal and umbilical serum in the acidemia group were significantly higher than that in the normal group, as were the same between the asphyxial group and the normal group, P < 0.01. The level of umbilical lactic acid was significantly higher than those groups, P < 0.01, but the maternal serum level of lactic acid was not, P > 0.05. Only ACTA in maternal serum was significantly different between the clear group and the meconium group, P < 0.05. Conclusion: The level of ACTA in the serum was a better index to predict fetal acidemia than lactic acid.It is a new index to predictive fetal distress.

【关键词】 ACTA乳酸胎儿窘迫
【Key words】 active Alactic acidfetal distress
  • 【文献出处】 岭南急诊医学杂志 ,Lingnan Journal of Emergency Medicine , 编辑部邮箱 ,2007年03期
  • 【分类号】R714.5
  • 【被引频次】3
  • 【下载频次】29
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