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呼吸性煤尘与尘肺的剂量-反应关系分析

Study on the dose-response relationship between respirable coal dust and pneumoconiosis

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【作者】 王欣平刘铁民

【Author】 WANG Xin-ping1,LIU Tie-min2(1.Capital University of Economics and Business,Beijing 100026,China)(2.China Academy of Safety Science and Technology,Beijing 100029,China)

【机构】 首都经济贸易大学中国安全生产科学研究院 北京100026北京100029

【摘要】 分析6个煤矿3082名煤尘接尘工人,其中包括51名尘肺患者接尘资料,首先通过比例换算法,按总煤尘EIC/TWA为1.5、总煤尘TWA/呼吸性煤尘TWA为3.82,将总煤尘EIC转换为呼吸性煤尘TWA;再用寿命表法分析累计接尘量与尘肺发病的剂量-反应关系,得到回归方程logit=5.714lgd-18.902(r=0.939),采用区间估计法,得接尘30年尘肺累计发病率为1%时,呼吸性煤尘TWA为6.52mg/m3,对估算结果取1.2的安全系数,呼吸性煤尘接触浓度管理限值为5mg/m3。

【Abstract】 This paper analyzed the data of 3082 workers exposed to coal dust and 51 pneumoconiosis in six mines.Firstly,according to the Environmental Instantaneous Concentration /the Time Weighted Average of total coal dust being 1.5 and the Time Weighted Average of total coal dust/the Time Weighted Average of respirable coal dust being 3.82,the Environmental Instantaneous Concentration of total coal dust was converted into the Time Weighted Average of respirable coal dust,secondly,life-table was applied to analyze the dose-response relationship between the cumulative dust exposed and the incidence of pneumoconiosis,get regression equation logit=5.714lg d-18.902(r=0.939),according to the interval estimate,when workers exposed to coal dust 30 years,the cumulative incidence of pneumoconiosis being 1%,the Time Weighted Average of respirable coal dust is 6.52 mg/m3.Devide the outcome by safety coefficient of 1.2,the Authorized Limit-Personal Exposure Concentration of respirable coal dust is 5mg/m3.

【基金】 国家科技支撑计划项目(编号:2006BAK05B04)资助
  • 【文献出处】 中国安全生产科学技术 ,Journal of Safety Science and Technology , 编辑部邮箱 ,2007年02期
  • 【分类号】R135.2
  • 【被引频次】9
  • 【下载频次】222
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