【摘要】 目的观察复方樟柳碱II号治疗眼外肌麻痹的临床效果。方法将40例(40只眼)后天性眼外肌麻痹患者(已排除颅内占位及脑梗塞、重症肌无力)随机分为复方樟柳碱II号治疗组及激素联合维脑路通对照组,每组各20例(20只眼)。治疗组用复方樟柳碱II号2ml行患眼颞浅动脉旁皮下注射,每天1次,10d为1个疗程,根据病情连续治疗2~4个疗程;对照组口服强的松20mg,每天1次,口服维脑路通200mg,每天3次,10d为1个疗程,根据病情连续治疗2~4个疗程;观察两组病例复视消失时间、眼位及眼球运动恢复情况。结果治疗组20例中治愈18例(90%),好转1例,无效1例,总有效率95%;对照组20例中治愈12例(60%),好转5例,3例无效。两组治愈率有显著性差异(P<0.05)。结论复方樟柳碱II号治疗眼外肌麻痹能明显提高治愈率,无并发症,安全有效。更多还原

【Abstract】 Objective Review the effect of compound Anisodine Hydrobromide II in treatment ophthalmoparalysis.Methods 40 cases of acquired ophthalmoplegia (exclusion Intracalvarium and rhinopharynx desease, myasthenia gravis) were invided into 2 groups in random. Therapy group use compound Anisodine Hydrobromide II and control group use troxerutin; venoruton respective.20 cases each group. Therapy group carry out arterial temporalis superficialis side hypodermic injection in trouble eye with 2ml compound Anisodine Hydrobromide II, qd, 10 days a course.carrry out 2~4 course based on patient’s condition. In control group, carry out prednisone 20mg, oraly,qd, and venoruton 200mg, t.i.d, 10 days a course. To observe the diplopia extinction time, position of eye and ocular movement recover status. Results In therapy group, curing 18 cases (90%), improve 1 cases, inefficacy 1 cases, total effective rate is 95%. In Control group, curing 12 cases (60%), improve 5 cases, inefficacy 3 cases, total effective rate is 85% .The cure rate was significant difference between 2 groups.Conclusion Treatment with compound Anisodine Hydrobromide II is a safe way for ophthalmoparalysis, it can raise cure rate and has no complication.更多还原