【摘要】 目的探讨感染性心内膜炎(IE)的基础病因、致病微生物、临床特征及治疗结果等因素,提高IE的诊治水平。方法对119例IE患者的基础病因、临床特征、致病微生物、治疗效果等临床资料进行回顾性分析。结果①基础病因中先天性心脏病比例最高(48例,40.3%),其次为风湿性心脏瓣膜病(36例,30.3%),无基础心脏病变有所增加(22例,18.5%)。②发热仍是IE最常见的临床表现(106例,89.1%)和首发症状(95例,79.8%),28例(23.5%)患者以心功能不全为主要症状。③98例患者做血培养,阳性率为63.1%(62例),其中链球菌27例(43.5%),葡萄球菌26例(41.9%)。④28例经胸超声心动图检查未发现赘生物的患者中11例(39.3%),手术发现赘生物,术后行病理检查均符合IE的病理诊断标准。结论基础病因中无基础心脏病变比例明显增加;葡萄球菌感染呈增多趋势。更多还原

【Abstract】 Objective:To improve the diagnosis and treatment of infective endocardits (IE) by exploring its causes, pathogenic microorganism, clinical characteristics and therapeutic result.Method:The clinical data of one hundred and nineteen inpatients with IE from July 1996 to August 2006 year in Tongji Hospital were retrospectively analyzed.Result:①The underlying heart diseases included the rheumatic heartdisease (30.3%) and congenital heart disease (40.3%), and there was no previously known heart disease in 18.5% of the cases. ②Fever was the most common (89.1%) and initial symptom (79.8%), and cardiac insufficiency was also the primary symptom (23.5%). ③Positive blood culture was found in 62 out of 98 cases(63.1 %):streptococcus (43.5%),staphylococcus (41.9%). ④Vegetation was found during cardiosurgery in 11 cases (39.3%) of 28 cases which were not found vegetation through TTE, and postop patho-examination accorded with patho-diagnostic criteria of IE. Conclusion:Staphylococcus infection was increased in the IE. The rates of no previously known heart disease increases.更多还原