【摘要】 目的初步研究以出血为首发症状的脑动静脉畸形的自然史。方法通过采集782例脑动静脉畸形病例的病史资料,并对其中104例未接受任何手术或放射治疗的以出血为首发症状的AVM病例随访,然后对病史资料及随访资料进行统计和分析。结果诊断后的3年死亡率为7.5%。影响再出血的危险因素为AVM位置,位于深部者更易再出血。就诊后第一年再出血率为10%,3年再出血率为19.6%。再出血死亡率为13.3%。随访患者无1例有后期癫癎发作。出血后不伴有神经功能障碍的患者无1例后期致残。结论首发症状为出血的AVM再出血的危险性与AVM位置有关。由出血导致的癫癎发作及神经功能障碍预后较好。更多还原

【Abstract】 Objective To analyse the natural history of brain arteriovenous malformations(AVM) whose first symptom was haemorrhage. Methods The natural history of brain arteriovenous malformations was studied in 782 patients. All patients’ data were obtained by their case histories. The 104 patients whose first symptom were haemorrhage managed nonsurgically and nonradiotherapy were followed for average 5.5 years, and analyse all data with statistics.Results The dangerous factor of rehaemorrhage are location of Avms. There was a 10% risk of rehaemorrhage in the first year after diagnosis, and 19.6% in three years after diagnosis. Three-year mortality rate after diagnosis is 7.5%. Conclusions The risk of rehaemorrhage is correlated with its location. Epilepsy and neurological handicap caused by haemorrhage have better prognosis.更多还原