【摘要】 研究核苷类似物联合人工肝治疗慢性乙型重型肝炎疗效。将58例慢性乙型重型肝炎患者分为三组,核苷类似物联合人工肝治疗组、单用人工肝治疗组、单用核苷类似物治疗组,观察治疗效果。联合治疗组病死率22.22%,胆红素下降明显,白蛋白回升,凝血酶原活动度好转,HBV DNA转阴或载量下降。血浆置换治疗可降低血清HBV DNA水平。核苷类似物联合人工肝治疗可加快肝功能好转,缩短病程,降低病死率,降低血清HBV DNA水平。更多还原

【Abstract】 To study the efficacy of nucleosides plus artificial liver support system(ALSS) on treating chronic severe hepatitis.58 patients with chronic severe hepatitis B were divided into three groups: combined treating group with nucleosides plus ALSS,ALSS treating group and nucleosides treating group.The therapeutic efficacy was observed.In combined treating group,mortality was 25%,and liver function indexes,such as bilirubin,albumin,prothrombin time activity(PTA),and HBV DNA level,improved.Treating with nucleosides plus ALSS could accelerate the amelioration of liver function,shorten course of disease,decrease mortality and HBV DNA level.更多还原