【摘要】 目的:分析20世纪80年代到21世纪初外科治疗喉癌的远期效果,并且探讨影响预后的因素。方法:应用回顾性调查的方法对315例喉癌患者进行分析,统计患者的生存率和死亡原因。结果:生存5年以上者233例,死亡60例,失访22例。累计生存率曲线统计5年生存率为73.97%,其中早期(Ⅰ期、Ⅱ期)为82.69%,晚期(Ⅲ、Ⅳ期)为62.64%。不同分型的5年生存率分别为声门上型73.76%,声门型82.55%,声门下型55.56%,跨声门型68.75%。喉部分切除术的5年生存率79.89%,喉全切术的5年生存率61.03%。患者5年内死亡的主要原因是局部复发和颈淋巴结转移。结论:早期诊断是提高喉功能保留手术比例和提高生存率的关键,严格掌握各术式适应证,保留足够的安全切缘并加强术后随访是提高生存率的根本。更多还原

【Abstract】 Objective:To investigation the clinic long -term result and explore the prognostic factor of patients with laryngectomy .Method:Three hundred and fifteen patients with laryngectomy were analysed. The survival rate and the cause of death were collected from this study.Result:Five years later, 233 cases were still alive, 60 cases were dead, 22 cases failed to be followed -up. Overall 5-year survival rate was 73.97%, 5-year survival rate for patients of early stage was 82.69%. Whereas, for patients of late stage was 62.64%.Five year survival rate for patients of superaglottic carcinoma, glottic carcinoma, subglottic carcinoma and transglottic carcinoma was respectively 73.76%, 82.55%, 55.56%, 68.75%. Five year survival rate for patients with partial laryngectomy was 79.89%, whereas, for total larynectomy was 1.03%.The cause of death were local recurrence and cervical glands metastasis. Conclusion:Early diagnosis was the key points to both larynx preservation and survival rate. for improving survival rate ,we should handle the indications strictly, remaine sufficient security cutting edge and follow -up visit.更多还原