【摘要】 目的了解新疆地区过敏性鼻炎患儿过敏原的分布状况,为儿童过敏性鼻炎的防治提供科学依据。方法采用体外特异性过敏原检测试剂盒(IVT)对104例过敏性鼻炎患儿进行吸入过敏原(IVT701)检测,其中88例患儿同时行食物过敏原(IVT702)检测。结果104例过敏性鼻炎患儿IVT701测试总阳性率73.1%,以蒿属植物最高38.5%,其后依次为榆杨柳树31.7%,豚草(巨大豚草、普通豚草)20.2%,霉菌(点青霉、交链孢霉、黑根霉)14.4%,螨(粉螨、尘螨)11.5%,屋尘7.7%等。88例患儿IVT702的总阳性率为56.8%,过敏原主要为大豆、花生28.4%,其次为鳕鱼和鸡蛋,分别为15.9%、13.6%,蟹虾为11.4%,牛奶和牛羊猪肉分别为5.7%和4.5%。65例患儿对2种及2种以上过敏原过敏。蒿属的阳性率随年龄的增长而增长(χ2=4.662,P<0.050)。结论蒿属为新疆地区过敏性鼻炎患儿最主要的过敏原,食物过敏亦占相当比例。明确过敏原后对特异性免疫治疗具有重要的指导意义。更多还原

【Abstract】 Objectives To analyse the allergens in children with allergic rhinitis and provide scientific basis for prevention and treatment in Xinjiang. Methods One hundred and four children with allergic rhinitis were recruited for the reactions to IVT701 and 88 cases of them had the IVT702 test at the same time with serum- specific IgE. Results The total positive rate of IVT701 tests were 73.1 %(76 cases) among the 104 cases with allergic rhinitis. The positive rate of artemisia 38.5 %(40 cases) was the highest. The positive rates of other allergens were tree(elm,poplar,willow) 31.7 %(33 cases),ragweed 20.2 %(21 cases), fungi 14.4 %(15 cases), mites 11.5 %(12 cases), house dust 7.7 %(8 cases). The total positive rate of IVT702 tests were 56.8 % among the 88 cases with allergic rhinitis. the positive rate of reaction to pea and peanut 28.4 %(25 cases)was the highest. The positive rates of cod fish,heneggs,crab and shrimp,cow’s milk,meat (beef,mutton,pork) were 15.9 %,13.6 %,11.4 %,5.7 % and 4.5 % respectively. Moreover, 65 cases were allergic to two or more allergens and the positive reaction rate to artemisia increased with the age of children,χ2 = 4.662,P < 0.05. Conclusions The artemisia is the most common allergen in the children with allergic rhinitis in Xinjiang. Food allergic is common as well. Children with allergic rhinitis should avoid taking into allergens. The results may provide the guideline to specific immunotherapy,in particular desensitization treatments.更多还原