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黄花败酱总皂苷提取物抗肿瘤作用的实验研究
Experimental research on the function of anti-cancer in the saponins from Patrinia scabiosaefolia Fisch
【摘要】 目的:观察黄花败酱总皂苷提取物体内抗肿瘤活性。方法:用MTT法观察黄花败酱总皂苷对荷艾腹水癌小鼠的生命延长率。结果:黄花败酱总皂苷对荷艾腹水癌的小鼠存活时间有一定的延长作用。结论:黄花败酱总皂苷有效成分有一定的体内抗肿瘤活性,其作用机制还有待进一步研究。
【Abstract】 Objective:To observe the in vivo cycotoxic effects of the saponins extracted from Patrinia scabiosaefolia Fisch.Methods:MTT assay was used,and the inhibitory effects of the saponins from Patrinia scabiosaefolia Fisch on Ehrlich Ascit carcinoma were observed in mice with peritoneal inoculation of the tumor cells.Results:The saponins from Patrinia scabiosaefolia Fisch could prolong the survival of mice with Ehrlich Ascites carcinoma.Conclusions:The saponins from Patrinia scabiosaefolia Fisch possesses antitumor effects in vivo.But its mechanism should be further studied.
【关键词】 MTT法;
小鼠移植性肿瘤;
黄花败酱总皂苷;
【Key words】 MTT method; mouce transplantation tumor; Patrinia scabiosaefolia Fisch;
【Key words】 MTT method; mouce transplantation tumor; Patrinia scabiosaefolia Fisch;
【基金】 省教育厅骨干教师课题,课题编号:1054G54
- 【文献出处】 黑龙江医药科学 ,Heilongjiang Medicine and Pharmacy , 编辑部邮箱 ,2007年03期
- 【分类号】R285.5
- 【被引频次】36
- 【下载频次】292