【摘要】 目的研究Univent导管在模拟肺以及临床条件下测定气管内压力的可行性。方法在模拟肺上,在呼吸机不同参数设定值时洁净Univent管测定气管导管两端的压力,导管远端压力用支气管阻塞管测定。之后在导管腔内注入1ml和2ml模拟分泌物,比较导管两端压力的改变;对10例病人进行了临床可行性评价,对气管导管两端压差以及压力波形进行测定和描记。结果在模拟肺研究中,洁净导管时Y接头和导管远端之间无显著压力差(P>0.05),在注入1ml和2ml模拟分泌物后导管两端压差分别增加到(4±2.67)mmHg和(5.79±3.68)mmHg(P<0.01)。在临床中使用Univent导管可以方便测定气管两端的压力,导管远端和近端压力差异显著(P<0.01)。远端压力改变明显慢于近端压力改变。结论气管导管近端压力无法准确反映导管远端压力,U-nivent导管可以用于气管内压力的直接测定。更多还原

【Abstract】 Objective To investigate the feasibility of direct tracheal pressure measurements with Univent tube in a model lung as well as under clinical circumstance.Methods In a lung model,proximal and distal pressures of endotracheal tube at different ventilator settings were measured in a clean Univent tube. Bronchial blocker was used to measure tracheal pressure.After that,1 ml and 2 ml gel were injected into the Univent tube’s lumen successively.Thus,fluctuations of pressures were observed.The clinical evaluation of Univent tube for direct tracheal pressure measurements were tested in ten patients.Pressure gradient of proximal and distal end of Univent tube was measured,and pressure waveforms were evaluated.Results There wasn’t a significant pressure difference across the clean tube. When injecting 1 ml and 2 ml gel into the Univent tube’s lumen ,the pressure gradient increased to 4±2.67mmHg and 5.79±3.68mmHg respectively (P<0.01).In clinical study ,significant pressure gradients between proximal and distal end of tube existed(P<0.01).The tracheal pressure changed much more slowly when comparing with proximal end in the pressure trace.Conclusion Pressure measured at proximal of tracheal tube can’t reflect tracheal pressure; Univent tube can be used to measure direct tracheal pressure.更多还原