【摘要】 目的评估肝动脉化疗栓塞(TACE)联合CT引导下经皮穿刺瘤内无水乙醇注射术(PEI)对中晚期肝癌的疗效。方法74例经证实为原发性中晚期肝癌随机分成3组,其中35例采用TACE+PEI治疗(TACE+PEI组),22例单纯采用TACE治疗(TACE组),17例单纯采用PEI治疗(PEI组)。动态监测肝功能、甲胎蛋白变化,CT或B超下瘤体大小变化,胃纳的变化以及腹部体征。结果3组疗效存在明显差异,TACE+PEI组的显效率+有效率明显高于单纯TA-CE组和单纯PEI组,且不良反应发生率低于单纯TACE组和单纯PEI组。结论TACE联合无水乙醇治疗中晚期肝癌,安全可行,较单独使用TACE或PEI治疗达到了更好的局部治疗效果,提高了患者生存质量,延长了存活时间。更多还原

【Abstract】 Objective To appraise the effect of transcatherter arterial chemoembolization(TACE) combined with percutaneous ethanol injection(PEI) for hepatoma.Methods There were 74 cases of mid-terminal primary hepatoma who were randomly divided into 3 groups,among which 35 cases were treated with TACE+PEI,22 cases were treated with simple TACE,and 17 cases were treated with simple PEI.The hepatic function,α-fetoprotein,the diameter of tumor body under B ultrasound or CT scan,appetite and abdomen appearance were detected dynamically.Results There were significant different among 3 groups about effects,among which the excellant and effective rate of TACE+PEI group were higher than that of simple TACE group and PEI group,and the complication rate was less in simple PEI group than that of TACE+PEI group and simple TACE group.Conclusion TACE matched with PEI is safe and effective for mid-terminal hepatoma,which improves the survival quality and prolongs survival time of hepatoma.更多还原