【摘要】 目的探讨通心络对冠脉支架术后C反应蛋白(CRP)变化以及临床预后的影响。方法对2003年1月-2004年12月期间就诊于我科的132例冠心病患者(包括急性心肌梗死,不稳定型心绞痛,稳定型心绞痛)随机分为通心络组(62例)和对照组(70例);对照组给予常规治疗,通心络组在常规治疗的基础上联合应用通心络6个月。结果术后6个月,通心络组的CRP明显低于对照组,主要心血管事件发生率明显低于对照组,但两组复查冠脉造影病例中再狭窄率无明显差异。结论通心络可降低冠脉支架术后CRP水平,改善临床治疗效果和预后。更多还原

【Abstract】 Objective To investigate the effects of Tongxinluo on C reactive protein(CRP)and clinical prognosis in patients after coronary stenting. Methods From January 2003 to December 2004, 132 patients in our department diagnosed as coronary artery disease(including acute myocardial infarction, unstable angina pectoris and stable angina pectoris)were divided into two groups: Tongxinluo group and control group. The control group received routine treatment, while Tongxinluo group based on routine treatment was administrated with Tongxinluo capsule in combination for 6 months. Results CRP level was much lower in Tongxinluo group together with apparent decrease of the major adverse cardiac event(MACE)rate in 6 months’ follow-up than those of the control group, but showing no difference in coronary arterial restenosis between the two groups at 6 months after coronary stenting. Conclusion Tongxinluo has favorable effects to decrease the CRP level and improve clinical efficiency together with prognosis for patients after coronary stenting.更多还原