节点文献
谷胱甘肽滴眼液与乃奇安治疗老年性白内障的随机对照研究
Randomized Controlled Study of The Anti-Cataract of Glutathione Ophthalmic Solution Compared with Neuthione in Patients with Senile Cataract
【摘要】 目的评价国产谷胱甘肽滴眼液对老年性白内障的临床疗效及安全性。方法175例白内障患者以3/2的比例随机分为两组,分别点国产谷胱甘肽滴眼液或乃安奇1~2滴,tid,疗程6个月。结果国产谷胱甘肽滴眼液与乃安奇组的视力有明显的改善(P<0.01)两组的总有效率为分别48.57%和44.28%(P>0.05)。两组药物的不良反应轻微,发生率分别为19.05%、8.57%(P>0.05)。结论谷胱甘肽滴眼液是治疗老年性白内障安全、有效的药物。
【Abstract】 Aim To evaluate the safety and efficacy of domestic glutathione ophthalmic solution in the clinical treatment of patients with senile cataract.Methods 175 patients with senile cataract were selected and at a ratio of three to two randomly divided into the glutathione ophthalmic solution group and the neuthione group.Each of them,respectively,received treatment of domestic glutathione ophthalmic solution and neuthioe by instilling 1 to 2 drops in the eye 3 times daily,for 6 months.Results The eyesight of the glutathione ophthalmic solution group and neuthione group was significantly improved(P< 0.01).The clinical efficacy rate of glutathione ophthalmic solution and neuthione was 48.57% and 44.28%(P>0.05),respectively.The adverse drug reactions of both groups were mild at 19.05%,8.57%,respectively.Conclusion This results suggest that glutathione ophthalmic solution is a safe and effective anti-cataract drug.
【Key words】 Glutathione ophthalmic solution; Neuthione; Senile cataract;
- 【文献出处】 解放军药学学报 ,Pharmaceutical Journal of Chinese People’s Liberation Army , 编辑部邮箱 ,2007年03期
- 【分类号】R776.1
- 【被引频次】8
- 【下载频次】99