【摘要】 目的探讨喉及喉咽部非上皮源性恶性肿瘤的临床病理特点、诊断及治疗。方法对1979年-2002年收治的10例喉、喉咽部非上皮性恶性肿瘤的临床病理特点、诊断及治疗进行回顾性分析。原发灶位于喉部者8例,其中喉肉瘤5例,恶性淋巴瘤2例,髓外浆细胞瘤1例;位于喉咽部者2例,其中原发癌肉瘤1例,胃恶性淋巴瘤扩散1例。所有患者采用手术切除,辅以放疗和/或化疗。结果1例失访,2例无瘤生存分别超过7年和8年,7例无瘤生存1年-6年后死亡。结论喉、喉咽部非上皮源性恶性肿瘤少见,预后较差,诊断必须结合免疫组织化学检查,并根据不同的类型选择治疗方法。更多还原

【Abstract】 Objective To investigate the clinicopathologic features,diagnosis and treatment of non-epithelial malignant tumors of larynx and hypopharynx. Methods From 1979 to 2002,the clinicopathologic features,diagnosis and treatment of 10 patients with non-epithelial malignant neoplasmas of larynx and hypopharynx were retrospectively analyzed.Primary lesions of 8 cases located at larynx whose pathological types included 5 sarcomas,2 lymphomas and 1 extramedullary plasmacytoma;Lesions of 2 cases located in hypopharynx.whose pathological types included 1 primary carcinosarcoma and 1 metastatic carcinoma diffused from stomach through lymphoma.All patients were treated with surgery combined with radiotherapy and/or chemotherapy. Results 2 patients with free-neoplasm have outlived for 7 years or 8 years respectively;other 7 patients with free-neoplasm had died in 1-6 years after surgery;and 1 case lost follow-up. Conclusion Non-epithelial malignant neoplasm in larynx and hypopharynx is uncommon and has poor prognasis.Immunohistochemistry staining is helpful for the final diagnosis.The therapy must differ from different types of tumors.更多还原