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藻酸双酯钠在寒冷性多形红斑治疗中的疗效观察
Evaluation of the efficacy of polysaccharide sulfate in treating patients with cold erythema multiforme
【摘要】 目的观察藻酸双酯钠治疗寒冷性多形红斑的疗效和安全性。方法对寒冷性多形红斑患者,以口服藻酸双酯钠100mg,每日3次;西替利嗪片10mg,每日1次及外用复方维生素E乳膏治疗为治疗组,并以单纯口服西替利嗪片10mg,每日1次及外用复方维生素E乳膏治疗为对照组,疗程14d,进行对比观察。结果共有40例患者纳入疗效分析,治疗组(n=20)及对照组(n=20)的总显效率分别为95%和70%(P<0.05),治疗组疗效明显优于对照组。结论联合应用藻酸双酯钠治疗寒冷性多形红斑具有较好的疗效。
【Abstract】 Objective To observe the efficacy and safety of polysaccharide sulfate in treating patients with cold erythema multiforme.Methods Using polysaccharide sulfate,cetirizine and compound vitamin E ointment to treat 20 patients with cold erythema multiforme as the treatment group compared with the control group in which 20 patients with cold erythema multiforme were given cetirizine and compound vitamin E ointment.The course of treatment in 2 groups was 14 d.Results Forty patients were eligible for efficacy analysis(20 in each group).The total significant recovery rate was 95% for treatment group and 70% for control group,respectively;the therapeutic effects of the treatment group were better than those of the control group(P<0.05).Conclusion Polysaccharide sulfate is an effective and safe agent in treating patients with cold erythema multiforme.
【Key words】 polysaccharide sulfate(PSS); cold erythema multiforme; therapeutic effects;
- 【文献出处】 中国海洋药物 ,Chinese Journal of Marine Drugs , 编辑部邮箱 ,2007年03期
- 【分类号】R758.61
- 【被引频次】2
- 【下载频次】68