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108例散发性戊型肝炎临床分析

The clinical analysis of 108 cases of sporadic hepatitis E infections

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【作者】 马英杰陈焕永姜宏齐张宇李庆刚

【Author】 MA Ying-jie,CHEN Huan-yong,JIANG Hong-qi,et al(Department of Infectious Diseases,The First Clinical College,Harbin Medical University,Harbin 150001,China)

【机构】 哈尔滨医科大学第一临床医学院感染科哈尔滨医科大学第一临床医学院感染科 黑龙江哈尔滨150001黑龙江哈尔滨150001

【摘要】 目的探讨散发性戊型肝炎的临床特点。方法对108例散发性戊型肝炎的分型、临床表现、血清生化及影像学等进行回顾性分析。结果重叠感染27例(25.0%);临床表现乏力(90.7%)、黄染(86.1%);60岁以上组血清谷丙转氨酶(ALT)、总胆红素(TBIL)与60岁以下组比较,差异有显著意义(P<0.05),重叠感染组血清TBIL、白蛋白(ALB)、γ-谷氨酸转肽酶(GGT)与单纯感染组比较,差异有显著意义(P<0.05);影像学肝脏弥漫性改变者68例(72.4%)。结论散发性戊型肝炎可与其他病毒性肝炎重叠感染,临床表现类似甲肝,老年患者、重叠感染者黄疸深、肝功能损害重,影像学改变与其他病毒性肝炎相似。

【Abstract】 Objective To explore the clinical characteristics of sporadic hepatitis E.Methods The clinical and etiological types,clinical findings,serum biochemistries,and the image characteristics in 108 patients with sporadic hepatitis E were retrospectively analyzed.Results There were 27 patients(25.0%)with superinfections;The symptoms were impotence(90.7%)and jaundice(86.1%);There was significant difference between the levels of ALT and TBIL in patients over 60-year-old and patients younger than 60-year-old(P<0.05),and the level of TBIL,ALB and GGT were significant difference between the groups with superinfection and without;In the image characteristics the livers of 68(72.4%) patients showed diffuse changes.Conclusion Hepatitis E could superinfect with other hepatitis viruses,the clinical findings of hepatitis E were similar to that of hepatitis A;the jaundices in the old patients or the patients with superinfection were heavy,and their liver functions were heavily damaged;the image characteristics of hepatitis E were similar to that of other viral hepatitises.

【关键词】 戊型肝炎黄疸影像学
【Key words】 hepatitis Eicterusimaging
  • 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,2007年03期
  • 【分类号】R512.6
  • 【被引频次】4
  • 【下载频次】75
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