【摘要】 [目的]评价体外受精-胚胎移植(IVF-ET)后12~14d血清β-HCG对妊娠结局的预测价值。[方法]回顾性分析我院行IVF-ET后妊娠的220例妊娠患者ET后12~14d血清β-HCG与妊娠结局的关系。[结果]血清β-HCG水平与妊娠结局相关。正常妊娠组血清β-HCG值高于不良妊娠组(P<0.01);多胎妊娠组血清β-HCG值高于单胎妊娠组(P<0.01)。以血清β-HCG<120mIU/ml作为不良妊娠预测标准,阳性预测值为90.0%,阴性预测值为87.9%;以β-HCG>600mIU/ml作为多胎妊娠预测标准,阳性预测值为84.6%,阴性预测值为91.1%。[结论]IVF-ET后12~14d血清β-HCG是早期预测妊娠结局的有效指标,可供正确指导咨询、及时处理参考。更多还原

【Abstract】 [Objective] To evaluate the predictive value of serum β-HCG in pregnancy outcome 12-14 days after in vitro fertilization-embryo transfer(IVF-ET).[Methods] The pregnancy outcome and serum β-HCG at 12-14 days after IVF-ET in 220 cycles were retrospectively analyzed.[Results] The levels of serum β-HCG were correlated with the pregnancy outcome.The serum β-HCG levels of normal pregnancies were higher than those of poor pregnancies(P<0.01)and levels of multiple pregnancies were higher than those of singleton pregnancies(P<0.01).Based on the cutoff value of β-HCG<120 mIU/ml in predicting poor pregnancy,the positive predictive value(PPV)was 90.0%,the negative predictive value(NPV)was 87.9%.Based on the cutoff value of β-HCG>600 mIU/ml in predicting multiple pregnancy,the PPV was 84.6%,the NPV was 91.1%.[Conclusion] The serum β-HCG at 12-14 days after IVF-ET is an effective predictor for pregnancy outcome,which may provide a reference for clinical counseling and management.更多还原