【摘要】 以4-羟基联苯为原料,经酯化、傅-克酰基化、相转移催化下的苄基化、氯仿反应、催化氢解等反应,合成了标题化合物,总收率57.8%。化合物4′-苄氧基-4-乙酰基联苯、4′-苄氧基-4-联苯甲酸的结构经1HNMR、IR、MS及元素分析确证。与文献比较,该路线选择性好、产率较高。更多还原

【Abstract】 4′-Hydroxy-4-biphenylcarboxylic acid was synthesized from 4-hydroxybiphenyl as the starting material via esterification,FriedelCrafts acetylation,benzylation under PTC,chloroform reaction,and catalytic hydrogenolysis,resulting in an overall yield of 57.8%.The structure of 4-acetyl-4′-benzyloxybiphenyl and 4-benzyloxy-4′-biphenylcarboxylic acid was confirmed by 1HNMR,IR,MS and elemental analysis.更多还原