节点文献

二次肾移植的效果及影响因素

Analysis of Effective Factors on Second Kidney Transplantation

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 王光策闫天中张翥陈铸屈淼林赵润璞陈潇雨

【Author】 WANG Guang-ce,YAN Tian-zhong,ZHANG Zhu,et al(The First Affiliated Hospital of Henan College of TCM,Zhengzhou 450000,China)

【机构】 河南中医学院第一附属医院移植泌尿科河南中医学院第一附属医院移植泌尿科 河南郑州450000河南郑州450000

【摘要】 【目的】探讨二次肾移植的效果及其相关影响因素。【方法】回顾分析46例二次肾移植病例,对二次移植的效果及切除与保留失功肾、距首次移植的时间对二次移植的影响进行分析。【结果】二次肾移植与首次移植的1、3、5年病人存活率方面无明显差异,但3、5年移植肾存活率明显下降,二次移植排斥反应发生率明显上升,以慢排为主;保留和切除失功肾及距首次移植时间对二次移植人/肾存活率及排斥反应均无明显影响。【结论】二次移植仍是移植肾失功后的首选治疗措施,其急排和慢排发生率较首次移植明显升高。失功肾的保留及距首次移植时间对排斥反应及人/肾存活率无明显影响。

【Abstract】 【Objective】To study the effective factors on second kidney transplant.【Methods】Forty six cases of second kidney transplantation were retrospectively analyzed.The survival rate in allografts and recipients between second transplant and primary transplant and between grafts removal and retention was compared and analyzed.【Results】The survival rates of recipients were similar in second and primary transplant,but the regraft survival rates in 3 and 5 years were poorer in second transplant significantly.The acute and chronic rejection in second transplant increased obviously,but not in super-rejection.No significant difference was seen in recipients/ regrafts survival rate and rejection between grafts removal and retention groups.【Conclusion】Second kidney transplantation is the optimal therapy after first graft failure.Rate of acute and chronic rejection is higher than first transplantation.Graft removal or retention and the duration between the first and the second kidney transplantation have little contribution for recipients/ regrafts survival rate and rejection.

【关键词】 肾移植
【Key words】 kidney transplantation
  • 【文献出处】 医学临床研究 ,Journal of Clinical Research , 编辑部邮箱 ,2007年07期
  • 【分类号】R699.2
  • 【被引频次】1
  • 【下载频次】114
节点文献中: 

本文链接的文献网络图示:

本文的引文网络