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口服葡萄糖耐量试验对肝硬化预后判断的临床观察

Clinic Observation for the Prognosis of Liver Cirrhosis with Oral Glucose Tolerance Test(OGTT)

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【作者】 符应征谭新忠

【Author】 FU Ying-zheng,TAN Xin-zhong(Department of Gastroenterology,the Second Hospital of Xiangtan 411100)

【机构】 湖南省湘潭市二医院消化内科湖南省湘潭市二医院消化内科 湖南湘潭411100湖南湘潭411100

【摘要】 【目的】探讨口服葡萄糖糖耐量试验(OGTT)对肝硬化预后的预测价值。【方法】将41例根据OGTT诊断的肝硬化病人分成三组进行前瞻性研究,观察患者的病死率和并发症发生情况,对预后有关的因素进行单元线性回归分析。【结果】糖代谢异常的患者各种并发症发生率和病死率明显高于糖代谢正常组,其预后较差。【结论】OGTT可作为除child分期标准以外判断肝硬化预后的有效指标。

【Abstract】 【Objective】To evaluate the predictive value of OGTT for the prognosis of liver cirrhosis.【Methods】Forty-one patients with liver cirrhosis were enrolled in three groups according to the result of OGTT,observing their complications and death causes and to investigate the variables of the cirrhosis-related prognosis using univariate regression models.【Results】The complication and death rate of diabetes mellitus(DM) were higher in patients with impaired glucose tolerance(NGT).Univariate analysis demonstrated that glucose intolerance was the same highly significant prognostic factor as serum albumin,total bilirubin,prothrombin activity and Child-Pugh scores.【Conclusion】OGTT is useful to evaluate the prognosis of liver cirrhosis.

【关键词】 肝硬化预后葡糖耐量试验
【Key words】 liver cirrhosisprognosisglucose tolerance test
  • 【文献出处】 医学临床研究 ,Journal of Clinical Research , 编辑部邮箱 ,2007年05期
  • 【分类号】R575.2
  • 【被引频次】9
  • 【下载频次】45
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