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急性冠状动脉综合征患者体内T细胞亚群的变化及活化

Activation and Changing of Tlymphocytes Composition in Acute Coronary Syndromes

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【作者】 崔颖李璐璐姜明

【Author】 CUI Ying,LI Lu-lu,JIANG Ming(Clinical Laboratory Contral,The Second Clinical Medical College of Harbin Medical University,Harbin 150080,China)

【机构】 哈尔滨医科大学第二临床医学院检验中心哈尔滨医科大学第二临床医学院检验中心 黑龙江哈尔滨150080黑龙江哈尔滨150080

【摘要】 目的研究T淋巴细胞是否参与了急性冠脉综合征(ACS)相关的炎症反应。方法采用流式细胞分析仪分析64例ACS患者和66例健康者循环T淋巴细胞亚群和T细胞激活标志物HLA-DR抗原的表达。结果ACS患者HLA-DR阳性的淋巴细胞数量显著高于健康者。结论ACS患者循环CD4+T淋巴细胞被激活,T细胞参与了ACS的发生。

【Abstract】 Objective To investigate whether circulating T lymphocytes took part in the Inflammatory reaction which related to acute coronary syndromes.Methods 64 patients with acute coronary syndromes,and 66 healthy subjects were studied.CD4+T lymphocytes and HLA-DR were investigated by flow cytometric analysis.Results The results demonstrated that the number of CD4+T cells and CD+DR+ cells in patients with acute coronary syndromes were higher(P<0.05) than those in control subjects.Conclusion These results suggestthat CD4+T cell were activated,and circulating T lymphocytes may play an important role in the development of acute coronary syndromes.

  • 【文献出处】 黑龙江医学 ,Heilongjiang Medical Journal , 编辑部邮箱 ,2007年02期
  • 【分类号】R541.4
  • 【被引频次】1
  • 【下载频次】20
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