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稀土元素铈对果蝇抗氧化酶活力的影响
Effect of Ce~(4+)on Activity of SOD and CAT in Drosophila melanogaster
【摘要】 目的观察不同浓度的硫酸铈培养基培养果蝇三龄幼虫超氧化物歧化酶(SOD)及过氧化氢酶(CAT)活力的变化。方法以不同浓度(1、4、16、64、256、1024mg/L)硫酸铈的培养基培养野生型黑腹果蝇,测定果蝇三龄幼虫SOD及CAT活力,并与基本培养基的对照组进行比较。结果与对照组比较,64~1024mg/L硫酸铈组果蝇SOD及CAT活力降低,差异有统计学意义(P<0.05,P<0.01),1~16mg/L硫酸铈组果蝇三龄幼虫SOD和CAT活力上升,差异有统计学意义(P<0.05,P<0.01)。结论Ce(SO4)2对果蝇具有一定的毒性效应。
【Abstract】 Objective To understand the effect of cerium on the activity of SOD and CAT in Drosophila melanogaster.Methods Drosophila melanogasters were treated with cerium by adding cerium sulfate [Ce(SO4)2] into the culture medium at different concentrations(0,1,4,16,64,256 and 1 024 mg/L).The activity of SOD and CAT of the third-instar larvae were analyzed.Result Compared with the control,at 64-1 024 mg/L,the activity of SOD and CAT in the third-instar larvae significantly decreased and at 1-16 mg/L,the activity of SOD and CAT significantly increased Conclusion It suggested that cerium sulfate [Ce(SO4)2] has an oxidant toxicity to Drosophila melanogaster.
【Key words】 Rare earth element; Drosophila melanogaster; Cerium; Lipid peroxidation;
- 【文献出处】 环境与健康杂志 ,Journal of Environment and Health , 编辑部邮箱 ,2007年03期
- 【分类号】Q966
- 【被引频次】4
- 【下载频次】257