Objective: To investigate the serum level of transforming growth factor β1(TGFβ1) and its clinical significance in patients with systemic lupus erythematosus(SLE).Method: Serum TGFβ1 from 48 SLE and 24 normal controls was measured using ELISA and analyzed accordingly.Result: Serum TGFβ1 level in the active SLE patients(759.51±425.04 pg/ml) was significantly lower than in the inactive SLE patients(1329.71± 415.82 pg/ml) or the controls(1364.83±201.96 pg/ml)(p<0.01,respectively).Serum TGFβ1 level inversely co...