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ICP-MS测定三种抗肿瘤中成药中铅镉汞砷含量

Determination of Pb, Cd, Hg and As in Three Sorts of Chinese Traditional Medicine Treating Tumor by ICP-MS

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【作者】 施丽飞; 薛大方; 徐恒瑰; 刘辉; 滕文锋;

【Author】 SHI Li-fei1, XUE Da-fang2, XU Heng-gui1, LIU Hui1, TENG Wen-feng1*1. Department of Chemistry, The Laboratory Medical College, Dalian Medical University, Dalian 116027, China2. Technical Center, Liaoning Administration for Entry Exit Inspection and Quarantine, Dalian 116000, China

【机构】 大连医科大学检验医学院化学教研室; 辽宁出入境检验检疫局技术中心; 大连医科大学检验医学院化学教研室 辽宁大连116027; 辽宁大连116000; 辽宁大连116027;

【摘要】 采用电感耦合等离子体-质谱(ICP-MS)法测定了三种抗肿瘤中成药(金克槐耳、华蟾素和复方苦参)中四种元素铅、镉、汞、砷的含量。结果显示,铅、镉、汞、砷四种元素在三种抗肿瘤中成药中的含量较低,均符合东南亚进口标准。其中金克槐耳中汞和砷含量略高于美国FAD药品与功能性食品要求标准,但仍符合其他标准。电感耦合等离子体-质谱法是测定中成药中铅、镉、汞、砷快速、准确的方法。

【Abstract】 A method was proposed to determine Pb, Cd, Hg and As in three sorts of Chinese traditional medicine treating tumor (Jinkehuaier, Huachansu and Fufangkushen) by ICP-MS. The result shows that the contents of the four elements Pb, Cd, Hg and As in these three sorts of Chinese traditional medicine treating tumor are low, which are all correspond with the import standard in Southeast Asia. The contents of Hg and As in Jinkehuaier are higher than the standard of U. S. FDA about drug and health food. ICP-MS is a quick and accurate method for the determination of Pb, Cd, Hg and As in Chinese traditional medicine.

【基金】 辽宁省教育厅高等学校科学研究项目(990221063)资助
  • 【文献出处】 光谱学与光谱分析 ,Spectroscopy and Spectral Analysis , 编辑部邮箱 ,2007年05期
  • 【分类号】R286.0
  • 【被引频次】26
  • 【下载频次】485
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