节点文献
将COX模型嵌入Markov链进行调整的生存质量分析
Quality adjusted survival analysis by Markov chain embedded with Cox model
【摘要】 目的将COX模型嵌入Markov链进行调整的生存质量分析。方法建立理论模型并通过实例进行分析。结果按照实例模型进行模拟数据,参数估计与原模型几乎一致。结论本方法通过对不同状态的生存时间加权求和,使不同处理的比较更合理,也使COX模型的应用更加灵活。
【Abstract】 Objective To carry out quality-adjusted survival analysis by Markov chain embedded with Cox model. Methods To construct theory models and analys by example. Results To simulate data according to the case model ,and parameter estimates are nearly consistent with the primary model. Conclusion Through integrating weighted sum of mean life time across all life states, it is become more reasonable to compare between different treatments, and more flexible to apply cox model.
【基金】 国家自然科学基金(30500421);广东省2004年第五批科技计划项目(26)
- 【文献出处】 广东药学院学报 ,Journal of Guangdong College of Pharmacy , 编辑部邮箱 ,2007年03期
- 【分类号】R195
- 【被引频次】4
- 【下载频次】174