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EMS患者治疗前后血清SIL-2R、TNF-α和CA199检测的临床意义

Clinical Significance of Determination of Changes of Serum SIL-2R, TNF-α and CA199 Levels After Treatment in Patients with Endometriosis

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【作者】 潘小利房瑜赵文娟

【Author】 Pan Xiaoli, Fang Yu, Zhao Wenjuan Lianyungang First People’s Hospital, Lianyungang, Jiansu (222002)

【机构】 江苏省连云港市第一人民医院妇产科江苏省连云港市第一人民医院妇产科 222002222002

【摘要】 目的:探讨子宫内膜异位症患者治疗前后血清SIL-2R、TNF-α和CA199水平的变化及意义。方法:应用放免法测定40例子宫内膜异位症患者血清TNF-α和CA199含量、酶联法测定SIL-2R含量,并与35名正常健康人作比较。结果:在治疗前,血清SIL-2R、TNF-α和CA199水平非常显著地高于正常人组(P<0.01),经治疗1个月后,与正常人组比较仍有显著差异(P<0.05)。结论:检测子宫内膜异位症患者血清SIL-2R、TNF-α和CA199水平的变化对其病情和预后判断均有重要的临床意义。

【Abstract】 Objective To investigate the clinical significance of changes of serum SIL-2R, TNF-α and CA199 levels after treatment in patients with endometriosis. Methods Serum SIL-2R, TNF-α and CA199 levels were detected with RIA and SIL-2R levels with ELISA in 40 patients with endometriosis both before and after treatment and 35 controls. Results Before treatment, the serum SIL-2R, CA199 and TNF-α levels were significantly higher in patients than those in controls (P<0.01). After treatment for one month. The serum SIL-2R, TNF-α and CA199 levels were much corrected but still remained significantly higher than those in the controls (P<0.05).Conclusion Determination of serum SIL-2R, TNF-α and CA199 levels in clinically useful in the management in patients with endometriosis.

  • 【文献出处】 放射免疫学杂志 ,Journal of Radioimmunology , 编辑部邮箱 ,2007年03期
  • 【分类号】R711.71
  • 【下载频次】49
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