【摘要】 目的:探讨金芪降糖片中主要成分黄芪、黄连对2型糖尿病患者血清P-SLT、TNF-α、血糖及糖基化血红蛋白(HbA lc)的作用及临床应用价值。方法:随机将糖尿病患者分为西药治疗对照组和金芪降糖片加西药治疗组,患者于治疗前后检测空腹与餐后2h血糖、糖基化血红蛋白(HbA lc)、血清P-SLT和TNF-α水平。结果:金芪组和对照组治疗前空腹血糖、餐后2h血糖、HbA lc、P-SLT和TNF-α水平比较无显著性差异(P>0.05),治疗后两组空腹血糖、餐后2h血糖均有明显下降;金芪组治疗后HbA lc、P-SLT、TNF-α水平明显降低,与治疗前及对照组比较均有差异(P<0.05、P<0.01、P<0.01)。结论:在常规西药治疗的基础上加用黄芪和黄连进行治疗,对于降低P-SLT、TNF-α及HbA lc水平,稳定血糖、预防或延缓微血管病变不失为一种较好的方法。更多还原

【Abstract】 Objective To study the effects of Huang Qi and Huang Lian on serum P-selectin,tumor necrosis factor-α(TNF-α),glucose and glycosylated hemoglobin(HbAlc) levels in patients with type two diabetes mellitus(DM).Methods Sixty DM2 patients were divided randomly into 2 eqnal numbered groups: one group were treated with routine hypoglycemic medicine,in other group,Jinqi hypoglycemic tablets wre added besides western medicine.Fasting blood glucose,two hour postprandial glucose,HbAlc,P-SLT and TNF-α levels were measured detected before and after three months’ treatment.Results There were no significant differences between the plasma glucose,HbAlc,P-SLT and TNF-α levels(P>0.05) in the JinQi group and western medicine group before treatment.Fasting plasma glucose and postprandial glucose were decreased after treatment in both groups.HbAlc,P-SLT and TNF-α levels were significantly decreased after treatment(P<0.05,P<0.01,P<0.01) in JinQi group.Conclusion On the basis of treatment with western medicine,additional Huang Lian and Huang Qi could further decrease HbAlc,P-SLT and TNF-α levels,stabilize blood glucose and provide better therapeutic results in patients with type 2 diabetes mellitus.更多还原