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胃内注入凝血酶治疗新生儿窒息后急性胃粘膜出血
Observation of the curative effect of thrombin injected into stomach to treat neonates with acute stomach mucous membrane bleeding after suffocation
【摘要】 目的:探讨胃管内注入凝血酶治疗新生儿窒息后胃粘膜出血的疗效。方法:将62例新生儿窒息后胃粘膜出血患儿随机分为对照组28例和观察组34例,观察组在常规洗胃后将凝血酶500 u溶于3~5mL生理盐水中经胃管注入胃内,每8h一次,至胃内出血停止。结果:观察组总有效率97.1%,对照组总有效率75.0%(P<0.05)。结论:胃内注入凝血酶对新生儿窒息后急性胃粘膜出血有较好的治疗作用。
【Abstract】 Objective:To probe into the curative effect of thrombin injected into stomach to treat neonates with stomach mucous membrane bleeding after suffocation.Methods: 62 infants with stomach mucous membrane bleeding after suffocation were divided at random into a control group of 28 and a treatment group of 34 with 500 u thrombin dissolved into 3~5 mL physiological saline injected into the stomach after washing the stomach in routine,once very 8 hours until the haemorrhage stopped. Results: The total curative effect of the treatment group was 33/34((97.1%),) while that of the control group was 21/28(75%),which had significant differences(P<0.05).Conclusions: Thrombin injected into the stomach has a good curative effect in the treatment of neonates with acute bleeding in mucous membrane of stomach after suffocating.
【Key words】 Thrombin; Neonates; Suffocation; The bleeding of mucous membrane of stomach;
- 【文献出处】 儿科药学杂志 ,Journal of Pediatric Pharmacy , 编辑部邮箱 ,2007年01期
- 【分类号】R722.152
- 【下载频次】33